Om Prakash
R&D Center of AVA Cholayil Health Care Pvt. Ltd, India
Title: Future innovation needed drug discovery in the next decade
Biography
Biography: Om Prakash
Abstract
It is not surprising that throughout history man has searched for remedies to fight against disease. Historically speaking, man has explored nature to satisfy two major needs – food and herbs for alleviating pain and suffering. Ancient civilizations had comprehensive treatises where herbs or mixtures of them represented the ‘‘corpus therapeuticum’’ to alleviate and treat disease. The challenge of discovering novel therapeutics is not getting any easier. One might imagine that with advances in technology, would come concomitant reduction in the discovery process. I know that I really don’t need to state that this is far from the truth. With significant uncertainty characterized by higher R&D costs, depleted pipelines and financial restrictions, the pharmaceutical industry can no longer function on its old model of closed innovation, stricter regulatory environments and the overall current economic downturn. This makes demands of all pharmaceutical companies to find better ways to increase their output of new drugs, through innovation, to both treat patients and meet their shareholders’ expectations. Pharmaceutical companies must find a better way to increase their output of truly new drugs for the benefit of patients and for their business survival. Here, we shall be elucidating a general perspective from within pharmaceutical research as it pertains to research advances in chemistry, biology, pharmacology, pharmacokinetics and toxicology that, if well integrated, stands to put the industry on a productive path. We should understand a new models like open innovation and ‘innovation ASAP’ (iASAP; asking powerful questions, seeking the outliers, accepting defeat and populating astutely).